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• Parental Rights, Best Interests and Significant Harms: Medical decision-making on behalf of children post Great Ormond St vs Yates.
• NTP Technical Report on the Toxicology and Carcinogenesis Studies of β-Picoline (CASRN 108-99-6) in F344/N Rats and B6C3F1/N Mice (Drinking Water Studies): Technical Report 580 [Internet].
  β-Picoline is used as a solvent in the synthesis of pharmaceuticals, resins, dyes, rubber accelerators, and insecticides. β-Picoline was nominated by the National Institute of Environmental Health Sciences for toxicological evaluation and carcinogenicity studies based on its high production volume and potential for human exposure. Male and female F344/N rats and B6C3F1/N mice were exposed […]
• NTP Technical Reports [Internet].
  Describe long-term studies that characterize and evaluate the toxicologic potential of selected test articles in animals.
• Standardized Library of Depression Outcome Measures [Internet].
  This document describes the technical approach used to prepare the Standardized Library of Depression Outcome Measures workbook. For reference, the narrative definitions for the minimum set of outcome measures produced by the Depression Workgroup are included in Appendix A.
• When to Initiate Antiretroviral Therapy, With Protocol for Rapid Initiation [Internet].
• Fluoxetine to improve functional outcomes in patients after acute stroke: the FOCUS RCT.
  Fluoxetine taken daily for 6 months after acute stroke did not improve patients’ functional outcome.
• Routine gastric residual volume measurement to guide enteral feeding in mechanically ventilated infants and children: the GASTRIC feasibility study.
  This study concluded that full trials in separate settings are feasible, but it is inappropriate to combine neonatal with paediatric intensive care due to differences in treatment protocols and outcome measures.
• Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT.
  Amiloride, fluoxetine and riluzole were not effective in reducing the brain volume loss in people with secondary progressive MS over 96 weeks.
• Prevention and treatment of venous thromboembolism in hospital and the community: a research programme including the ExACT RCT.
  This research programme found that extended anticoagulation therapy reduces recurrence of venous thromboembolism and is strongly preferred by patients, and identified barriers to implementation of thromboprophylaxis for hospital acquired thrombosis.
• Is Breast MRI Better at Finding Second Breast Cancers than Mammograms Alone for Breast Cancer Survivors? [Internet].
  Annually, more than 250 000 US women are diagnosed with breast cancer and are recommended for yearly surveillance mammography for second cancers after treatment completion. Many also receive breast magnetic resonance imaging (MRI), without evidence of effectiveness.